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Micofenolato de mofetila

CellCept, Myfenax, Myfortic

There are several brands of mycophenolate available and your treatment could be affected by switching between brands. Each time you collect a new supply from your pharmacy, please check to see if your medicine looks the same as before. If it is different, discuss this with your pharmacist who will advise you.

Taking mycophenolate could reduce your body's resistance to infections. Try to keep away from people who you know are ill, and report any sign of infection (raised temperature, cough) to your doctor.

It is important to protect yourself from serious illness by having any vaccinations your doctor offers you.

At a glance

  • Mycophenolate is a medicine to prevent the rejection of new organs after a transplant.

  • It suppresses your body's immune system to stop it from rejecting the new organ.

  • Take it exactly as prescribed by your doctor, usually twice a day.

  • Do not swap between different forms or brands of mycophenolate without medical advice.

  • This medicine can increase your risk of infections and sun sensitivity.

  • Women and men need to use contraception during and after treatment due to risks to an unborn child.

  • Let your doctor know about any new symptoms or side effects, especially fever or unusual bleeding.

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About mycophenolate

Tipo de medicamento

An immunosuppressant

Usado para

To prevent rejection of new organs following heart, kidney or liver transplants

Também chamado de

CellCept®, Myfenax® (as mycophenolate mofetil);
Ceptava®, Myfortic® (as mycophenolic acid)

Disponível como

Tablets, capsules, oral liquid medicine and injection

Mycophenolate is used to prevent the rejection of new organs following a transplant operation. Sometimes the body tries to reject new donor tissue and mycophenolate helps to prevent this rejection by suppressing your body's immune, or defence, system. It will be prescribed for you, along with other medicines to prevent rejection, by a transplant specialist doctor.

There are two different forms of mycophenolate; mycophenolate mofetil and mycophenolic acid. There are also a number of different brands of tablets and capsules. Ideally you should not swap between these different formulations, so each time you collect a new supply from your pharmacy, please check to make sure that it looks to be the same as you have had before.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking mycophenolate it is important that your doctor knows:

  • Se você está grávida, tentando ter um bebê ou amamentando.

  • If you have any problems with the way your kidneys work (unless this is the reason for the treatment).

  • If you are receiving any treatment for a problem with your digestive system.

  • Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

  • Se você já teve uma reação alérgica a um medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mycophenolate and how to take the brand of medicine you have been supplied with. It will also provide you with a full list of side-effects which you could experience from taking mycophenolate.

  • Take mycophenolate exactly as your doctor tells you to. It is usual to take a dose twice each day (morning and evening). The number of tablets or capsules for each dose will vary depending on the type of transplant you have had. Your doctor will tell you what dose is right for you and this will also be printed on the label of the pack to remind you.

  • If you have been given the oral suspension (liquid medicine), please measure out your dose using the oral dose dispensers provided.

  • You can take mycophenolate either before or after meals, but it is best if you stick to one or the other.

  • Swallow the tablet/capsule whole - do not crush or chew the tablets, and do not open the capsules before swallowing.

  • Try to take your doses at the same times of day each day, as this will help you to remember to take them. If you do forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.

  • Continue to take mycophenolate unless you are advised otherwise by your doctor. Stopping the treatment will increase the risk of your body rejecting the transplant.

  • Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have regular blood tests during the treatment.

  • Your doctor will discuss with you the possibility of a slightly increased risk of cancer associated with taking an immunosuppressant. While you are taking mycophenolate, you may become more sensitive to the harmful effects of sunlight, and as a result be at an increased risk of skin cancer. Because of this it is important that you do not use sunbeds, that you avoid strong sunlight, and that you protect yourself with a sun cream with a high sun protection factor (SPF of at least 15).

  • Mycophenolate could harm an unborn child. It is important that you do not become pregnant while you are taking mycophenolate. Women should use two methods of contraception from before the start of the treatment to six weeks after stopping the treatment. Please make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Men should use condoms during treatment and for 13 weeks after taking the last dose, and their partners should also use contraception during this same period.

  • Este medicamento reduz sua proteção natural contra infecções. É importante proteger-se de doenças graves tomando todas as vacinas que seu médico recomendar. Se você mora com outras pessoas, elas também podem ajudar a protegê-lo ao tomar suas próprias vacinas.

  • Algumas vacinas podem não ser adequadas para pessoas com sistemas imunológicos enfraquecidos. Sempre informe a pessoa que está vacinando que você está tomando este medicamento.

  • If you are due to have any treatment like an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking.

  • If you buy any medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with your other medicines. This is because some medicines (such as antacids and some vitamin preparations which contain iron) can interfere with the way mycophenolate works.

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Your doctor will have discussed with you the possibility of unwanted side-effects and how you will be regularly checked for signs of these. You will also have been told that you may become more prone to infections. Some of the most common unwanted effects of mycophenolate are listed below. Let your doctor know if any of the following continue or become troublesome, or if you experience any other symptoms which you are concerned about or think may be due to the medicine.

Very common mycophenolate side-effects (these effect more than 1 in 10 people)

O que posso fazer se passar por isso?

Increased susceptibility to infections (such as chest infections), high temperature, cough

Let your doctor know straightaway if you have a high temperature, a cough, or you feel generally unwell

Unexpected bruising or bleeding, skin rash

Let your doctor know straightaway about this

Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) pain, indigestion, wind (flatulence)

Mantenha-se em alimentos simples - evite refeições ricas ou picantes

Sentindo-se cansado ou tonto

Não dirija e não use ferramentas ou máquinas enquanto estiver afetado

Diarreia

Beba bastante água para repor os líquidos perdidos

Constipação

Drink plenty of water and eat a balanced diet with plenty of fruits and vegetables. Ask a pharmacist to recommend a suitable remedy.

Dor de cabeça

Beba bastante água e peça a um farmacêutico que recomende um analgésico adequado. Se as dores de cabeça continuarem, informe seu médico

Alterações em alguns exames de sangue

Your doctor will test for these

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

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Inseguro sobre misturar medicamentos?

Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.

Perguntas frequentes

Why is my mycophenolate tablet sometimes a different shape or colour?

There are different forms of mycophenolate, called mycophenolate mofetil and mycophenolic acid, and several brands of tablets and capsules. It's important to stick to the same formulation, so always check with your pharmacy to ensure the medicine you receive is the same as you've had previously.

Can I take mycophenolate with other medicines I buy from a shop?

Some over-the-counter medicines, herbal remedies, and even certain vitamins (like some iron preparations) can affect how mycophenolate works. Always check with a pharmacist to make sure any new medicine or herbal remedy is suitable to take with mycophenolate.

What should I do if I forget to take a dose of mycophenolate?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose and continue with your regular schedule. Never take two doses at once to compensate for a forgotten one.

How long will I need to take mycophenolate after my transplant?

You should continue taking mycophenolate for as long as your doctor advises. Stopping the treatment without medical instruction can increase the risk of your body rejecting the transplanted organ.

Does mycophenolate make me more likely to get sick?

Yes, mycophenolate works by suppressing your immune system, which means your body's natural protection against infection is lowered. This increases your susceptibility to infections. It's important to be vigilant for symptoms like high temperature, cough, or generally feeling unwell and to inform your doctor if these occur.

What precautions should I take regarding sunlight while on this medication?

Mycophenolate can make you more sensitive to sunlight, increasing your risk of skin cancer. You should avoid strong sunlight, not use sunbeds, and always protect your skin with a sun cream that has a high sun protection factor (at least SPF 15).

Are there any specific concerns for men taking mycophenolate about contraception?

Yes, men taking mycophenolate should use condoms during treatment and for 13 weeks after the last dose. Their partners should also use contraception during this same period because mycophenolate could harm an unborn child.

Leitura adicional e referências

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão prevista: 3 de Dez de 2027
  • 4 Dez 2024 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
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