Propionato de clobetasol para condições inflamatórias graves da pele
Clarelux, ClobaDerm, Dermovate, Etrivex
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 25 Abr 2024
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You only need to use a small amount of this preparation. Apply a small amount just to the areas affected, and then massage it gently into the skin.
Topical corticosteroids should not be used for long periods of time or on large areas of the body, especially in children. This is due to the risk of serious side-effects with long-term use.
As a guide, clobetasol should not be used continuously for more than 5 days in children and 7 days in adults, unless your doctor gives specific instructions to do so.
Clobetasol propionate (unless combined with an antibacterial agent) should not be used on any infected areas of skin.
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About clobetasol propionate
Tipo de medicamento | A very potent topical corticosteroid |
Usado para | Condições inflamatórias da pele, como eczema severo e dermatite |
Também chamado de | Clarelux®; ClobaDerm®; Dermovate®; Etrivex® |
Disponível como | Cream, ointment, foam, scalp application and shampoo |
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as esteroides tópicos. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema e dermatite. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Specialist skin doctors may on occasion prescribe a short course of clobetasol propionate for the treatment of psoriasis, although it is not generally recommended for this skin condition. Clobetasol propionate is not recommended for use in children, although again, it may be prescribed for a child by a specialist doctor under certain circumstances.
Clobetasol propionate is available as a number of different preparations. It is likely you will be prescribed a cream if the affected areas of your skin are moist or weeping, or an ointment if your skin is dry. It is also available as a shampoo and as an application for the scalp.
There is also a preparation available which contains two antibacterial agents called neomycin and nystatin. You may be prescribed this preparation for short-term use if your skin has become infected. It is typically used twice a day for one week only.
Before using clobetasol propionate
Voltar ao conteúdoTo make sure this is the right treatment for you, before you start using clobetasol propionate it is important that your doctor knows:
Se você tiver alguma área de pele infectada.
Se você tem rosácea ou acne.
Se você está grávida ou amamentando.
Se você já teve uma reação alérgica a uma preparação para a pele.
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How to use clobetasol propionate
Voltar ao conteúdoBefore you start using the preparation, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about topical steroids and will give you full instructions for using the preparation you have been given. It will also provide you with a list of the side-effects that you may experience.
Apply a small amount of cream/ointment to the areas of skin which are inflamed. Then gently rub it into the skin until it has disappeared. Do not use clobetasol propionate on any open sores or areas of infected skin unless you have a preparation which contains antibacterial agents (clobetasone with neomycin and nystatin). If you are using this preparation, use it regularly twice daily for one week only, unless you have been directed otherwise by your doctor.
The amount of topical steroid cream/ointment that you should apply is commonly measured by fingertip units (FTUs). One FTU is the amount of cream or ointment that is squeezed out along an adult's fingertip (that is, from the very end of the finger to the first crease in the finger). As a guide, one FTU is enough to cover an area twice the size of an adult hand. Your doctor will give you an idea of how many FTUs you will need to cover the area of your skin which is affected.
If you are using a scalp application, apply a few drops of liquid or a small amount of foam to the affected areas of your scalp, rub it in gently, and then allow the areas to dry again naturally. If you are using Etrivex® shampoo, apply a small amount to the affected areas of your hair when it is dry, massage it in gently, and then rinse it off after 15 minutes. As a guide to how much to use, half a tablespoon of shampoo (7.5 ml) is sufficient to cover the whole of your scalp.
If you are using Clarelux® cutaneous foam, hold the container upside-down so the nozzle is pointing downwards. Press the button to deliver a teaspoon-sized amount of foam directly onto the affected skin and gently massage the area until the foam disappears. Try not to spray the foam into your hands first as it will quickly start to melt. Avoid contact with the eyes, nose and mouth.
Your doctor will tell you how often to apply clobetasol propionate. It must not be applied more than twice a day, and once a day is often sufficient.
Se você estiver usando mais de um corticosteroide tópico, certifique-se de saber quando e onde usar cada um. Se estiver em dúvida, consulte seu médico ou peça mais orientações ao seu farmacêutico.
After you have applied clobetasol propionate, remember to wash your hands (unless your hands are the treated area).
If you are using clobetasol propionate for psoriasis, make sure you follow your doctor's instructions carefully. It should not be used for large areas of psoriasis or for long periods of time, as these can cause your symptoms to flare up again afterwards.
Clobetasol propionate is not suitable for use in children unless it is has been advised by a skin specialist. This is because children are particularly susceptible to side-effects from strong topical steroids. The main concern is for children who need frequent courses, as it can have an effect on their growth and this will need to be monitored. If your child has been prescribed clobetasol propionate, follow the directions you have been given very carefully, and do not use it for longer than you have been told to. As a general rule, it should not be used for more than five days in children.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoIf you are using a moisturiser along with this preparation, apply the moisturiser first. Then wait 10-15 minutes before applying clobetasol propionate. This allows time for the moisturiser to be absorbed before the topical corticosteroid is applied. Your skin should be moist but not slippery when you apply clobetasol propionate.
Do not use clobetasol propionate on your face.
A menos que seja orientado pelo seu médico, não aplique uma bandagem ou curativo na área sendo tratada, pois isso aumentará a absorção da preparação e o risco de efeitos colaterais.
Continue to use clobetasol propionate until the flare-up is controlled, and then stop it. A course of treatment for 7-14 days is usually sufficient. If your symptoms have not improved after this time (or if they get worse), speak again with your doctor for further advice.
After you finish using clobetasol propionate, continue to use your moisturiser every day. This will help to prevent a further flare-up. Your doctor may also prescribe a less potent steroid cream for you to use when needed.
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Can clobetasol propionate cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. You can reduce the risk of side-effects from topical corticosteroids like clobetasol propionate, by applying the preparation thinly, no more than twice a day, and to the affected areas only.
Side-effects of clobetasol propionate | O que posso fazer se passar por isso? |
A burning sensation or smarting | Esses podem ocorrer nos primeiros dias, mas geralmente melhoram depois disso |
Afinamento da pele, estrias permanentes, dermatite de contato alérgica, acne, rosácea e crescimento de pelos no local de aplicação | These would normally only affect you if you use clobetasol propionate for long periods of time |
Clobetasol propionate may get through your skin and into your bloodstream | This usually causes no problem unless you use clobetasol propionate regularly on large areas of your skin |
If you experience any other symptoms which you think may be due to clobetasol propionate, speak with your doctor or pharmacist for further advice.
How to store clobetasol propionate
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Certifique-se de que a pessoa que prescreve este medicamento saiba sobre quaisquer outros medicamentos que você esteja tomando ou usando. Isso inclui medicamentos que você compra e medicamentos fitoterápicos e homeopáticos.
Antes de usar este medicamento, informe ao seu médico se você já teve uma reação alérgica após tomar ou usar qualquer medicamento.
Nunca use mais do que a dose prescrita. Se suspeitar que alguém ingeriu o medicamento acidentalmente, entre em contato com o departamento de acidentes e emergências do hospital local para obter orientação.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando ou usando.
Se você comprar qualquer medicamento, verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

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Leitura adicional e referências
- Manufacturer's PIL, Dermovate® Cream; GlaxoSmithKline UK, O Compêndio Eletrônico de Medicamentos. Datado de agosto de 2023.
- Manufacturer's PIL, Dermovate® Scalp Application; GlaxoSmithKline UK, O Compêndio Eletrônico de Medicamentos. Datado de agosto de 2023.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 21 Fev 2027
25 Abr 2024 | Última versão

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