Can I take Clopodogrel and Isosorbate mononotrate together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
There is no direct harmful interaction between clopidogrel and isosorbide mononitrate. They are often prescribed together for heart conditions. However, both can contribute to a slight increase in the risk of bleeding or bruising, and isosorbide mononitrate can cause low blood pressure (dizziness), which may be more noticeable when starting new heart medications.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Clopidogrel is an antiplatelet medicine that stops blood cells (platelets) from sticking together to prevent clots. Isosorbide mononitrate is a nitrate that widens blood vessels to improve blood flow. They work in different ways and do not interfere with how the body processes (metabolises) each other.
What you should do
Back to contentsYou can safely take these medicines together as prescribed by your doctor. Be aware that you may bruise more easily. If you feel dizzy or lightheaded, especially when standing up, move slowly and stay hydrated. Seek medical advice if you experience any unusual or heavy bleeding.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Drug interactions checker
Can I take Pregabalin and Prozac together?
Taking pregabalin and Prozac (fluoxetine) together can increase the risk of side effects that affect your brain and nervous system. You may feel more drowsy, dizzy, or confused. It can also make it harder to concentrate or perform tasks that require alertness. In some cases, especially in older adults, it may lead to impaired thinking or coordination. There is also a small but serious risk of a rare condition called serotonin syndrome, which can cause shivering, sweating, and a fast heartbeat.
Drug interactions checker
Can I take Aspirin and Tramadol together?
Taking aspirin and tramadol together can increase the risk of bleeding, particularly in the stomach or gut. It may also increase the risk of side effects like dizziness, drowsiness, or feeling sick. Additionally, both medications can affect your kidney function, especially if you are dehydrated or have existing kidney issues.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.