Can I take Berberine and Milk thistle extract together?

Why this happens

Milk thistle (specifically the component silymarin) can slow down the proteins in the gut and liver that normally pump berberine out of cells or break it down. This allows more berberine to stay in your system for longer.

It is generally safe to take these together, but you should monitor yourself closely for side effects like digestive discomfort or signs of low blood sugar (dizziness, shaking). If you are taking medication for diabetes or blood pressure, speak to your doctor first, as this combination might make those medications more potent.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.