Can I take Aspire hayfever relief and Ibuprofen together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
There is no known interaction between Aspire Hayfever Relief (cetirizine) and ibuprofen. It is generally safe to take these two medicines together.
In this article:
Continue reading below
Why this happens
These drugs work in different ways and are processed by different parts of the body. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, while cetirizine is an antihistamine that blocks the effects of histamine during an allergic reaction. They do not interfere with each other's absorption or metabolism.
What you should do
Back to contentsYou can take these medicines together if needed. Always follow the dosage instructions on the packaging for each product. If you feel unusually drowsy, avoid driving or operating machinery.
Continue reading below
Important precautions
Back to contentsAsthma
Do not take this medicine if you have asthma, as it can cause a life-threatening worsening of your breathing or a severe allergic reaction.
Stomach ulcers or bleeding
Avoid this medicine if you have ever had a stomach ulcer, perforation, or bleeding, as it significantly increases the risk of serious internal bleeding.
Driving and operating machinery
Although classified as non-drowsy, this medicine can cause significant sleepiness in some people; do not drive or use tools until you are certain you are not affected.
Food and drink warnings
Back to contentsAlcohol
Drinking alcohol while taking ibuprofen can increase the risk of stomach irritation and gastric bleeding. It is best to limit alcohol intake or avoid it if you have a history of stomach issues.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Amitriptyline and Colecalciferol together?
There are no known significant interactions between amitriptyline and colecalciferol (Vitamin D3). It is generally considered safe to take these two medications together.

Treatment and medication
Can I take Allopurinol and Nortriptyline together?
There is no known direct interaction between allopurinol and nortriptyline. However, both medications can occasionally cause side effects that affect the liver or blood counts. Taking them together does not typically increase these risks, but it is important to be aware of how you feel.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.