Can I take Apixaban and Magnesium together?

Why this happens

Apixaban is an anticoagulant (blood thinner) that works by blocking a specific clotting factor. Magnesium is a mineral used for various bodily functions. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.

You can continue taking both as prescribed. However, always inform your doctor or pharmacist about all supplements you are taking. If you experience any unusual bruising or bleeding while taking apixaban, seek medical advice regardless of other supplements.

Bleeding risk and surgery

You must tell your doctor or dentist you are taking apixaban before any procedure or surgery, as it may need to be stopped temporarily to prevent dangerous bleeding. Seek immediate medical help if you have a serious fall or head injury.

Kidney disease

If you have severe kidney problems, you must not take magnesium supplements without medical supervision as levels can build up to toxic levels. Your dose of apixaban may also need to be reduced to prevent it from reaching dangerous levels in your blood.

Alcohol

While there is no direct chemical interaction, drinking alcohol can increase the risk of stomach bleeding while taking apixaban. It is best to keep intake within the recommended low-risk limits (no more than 14 units per week).

Dairy products and high-calcium foods

Taking large amounts of calcium (found in dairy products like milk, cheese, and yoghurt) at the same time as magnesium can reduce how much magnesium your body absorbs. If possible, try to take your magnesium supplement at a different time of day from high-calcium meals or supplements.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.