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Can I take Amlodipine and Rosuvastatin together?

Drug interaction guide

Taking amlodipine and rosuvastatin together may slightly increase the risk of muscle pain or weakness. While this combination is very common and generally considered safe, some patients may be more sensitive to the effects of the statin.

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Why this happens

Amlodipine can slightly interfere with the way the body processes certain statins, potentially leading to a small increase in the level of rosuvastatin in your bloodstream. This increases the chance of side effects affecting the muscles.

You can usually take these medicines together. However, you should inform your doctor if you experience any unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever. Your doctor will monitor your progress and may adjust your dose if necessary.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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