Skip to main content

Can I take Allergy and Ramipril together?

Drug interaction guide

Taking ramipril can make allergic reactions more severe and increases the risk of a rare but serious swelling reaction called angioedema. It can also interfere with allergy skin tests and certain allergy treatments (desensitisation).

Video picks for Drug interactions

Continue reading below

Why this happens

Ramipril is an ACE inhibitor. It works by blocking an enzyme that normally breaks down a substance called bradykinin. If you have an allergic reaction, levels of bradykinin and histamine rise. Because ramipril prevents these from being cleared away, the swelling and airway constriction can become much worse than usual.

If you have a known severe allergy (like a nut or bee sting allergy), tell your doctor before starting ramipril. If you experience any swelling of the face, lips, tongue, or throat while taking ramipril, stop taking it immediately and seek emergency medical help. If you are planning to have allergy skin testing or 'allergy shots' (desensitisation therapy), inform your specialist that you are taking an ACE inhibitor.

Continue reading below

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.