Can I take Accrete d3 and Cymbalta together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together may increase the levels of calcium in your blood (a condition called hypercalcaemia). While this is not common, it can lead to symptoms like feeling sick, constipation, or feeling very thirsty.
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Why this happens
Accrete D3 contains Vitamin D, which helps your body absorb calcium. Cymbalta (duloxetine) can occasionally affect how your kidneys handle minerals or change your fluid balance. In some cases, this combination can lead to higher-than-normal calcium levels in the bloodstream.
What you should do
Back to contentsIt is generally safe to take these together, but you should have your calcium levels checked regularly by your doctor as part of your routine blood tests. If you start to feel unusually tired, thirsty, or have persistent stomach pain, contact your GP.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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