Can I take 50 and Artovastatin together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking 5-HTP with atorvastatin may increase the risk of a rare but serious side effect called rhabdomyolysis. This is a condition where muscle tissue breaks down, which can lead to kidney damage. You may experience unexplained muscle pain, tenderness, or weakness.
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Why this happens
Both 5-HTP and atorvastatin can independently affect muscle health. While the exact mechanism of this specific combination is not fully documented, combining supplements that affect serotonin levels with statins can sometimes increase the risk of muscle toxicity (myopathy).
What you should do
Back to contentsYou should speak to your doctor before taking 5-HTP if you are already prescribed atorvastatin. If you are taking both and notice any unexplained muscle pain, dark-coloured urine, or unusual tiredness, stop taking the 5-HTP and contact your doctor immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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