Pressão alta aos 30 e poucos anos pode encolher seu cérebro
Revisado por Milly EvansÚltima atualização por Ashwin BhandariLast updated 21 de ago de 2019
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A rise in blood pressure between your 30s and 40s is linked to poorer brain health in later life, suggest researchers at University College London.
Patrocinado
Paciente recomenda... Hilo
Monitore sua pressão arterial continuamente, dia e noite - sem um manguito inflável. Os manguitos tradicionais capturam apenas um momento, se você se lembrar de usá-los. O Hilo realiza cerca de 25 leituras por dia, revelando como o estresse, as refeições e a atividade afetam sua pressão arterial, para que você possa tomar decisões informadas para o seu bem-estar.
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The team looked at lifelong data from 500 participants, who were all born in the same week in 1946, in order to assess demência risk. They also looked at a pressão arterial measurements taken throughout the participants' lives.
Brain scans looked for levels of a key Alzheimer's protein called amyloid. Brain size and presence of blood vessel damage in the brain were also taken into account.
An increase in blood pressure between the ages of 36 and 43 was linked to a decreased brain volume. Rises in blood pressure between the ages of 43 and 53 were also linked to blood vessel damage or 'mini-strokes' in people over 70. However, blood pressure was not associated with the amount of amyloid protein in the brain.
Lead author Professor Jonathan M Schott, University College London, said: "We now know that damage caused by high blood pressure is unlikely to be driven through the hallmark Alzheimer's protein amyloid, but through changes in blood vessels and the brain's architecture. The findings show that blood pressure monitoring and interventions aimed at maximising brain health later in life needs to be targeted at least by early midlife.
"NHS health checks are currently offered from the age of 40, and the uptake is, at most, 50%. Our data suggests that blood pressure should be measured much earlier," he told the BBC.
Dr Carol Routledge, director of research at Alzheimer's Research UK, said: "High blood pressure in midlife is one of the strongest lifestyle risk factors for dementia, and one that is in our control to easily monitor and manage. Research is already suggesting that more aggressive treatment of high blood pressure in recent years could be improving the brain health of today's older generations.
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Mais de 1 em cada 4 adultos tem pressão alta (hipertensão), uma condição que pode levar a danos nos rins, derrame e doenças cardíacas. É importante verificar sua pressão arterial regularmente. Mas se você já foi informado de que a sua está alta, estas dicas de estilo de vida podem ajudá-lo a reduzi-la.
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High blood pressure is affecting the under 50s more and more frequently - but why? We explore the lifestyle habits among Millennials that may be responsible for this rise. Whatever your age, by addressing these causes of high blood pressure, you can help keep your blood pressure healthy and try to avoid the serious health issues it can lead to.
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Patrocinado
Paciente recomenda... Hilo
Monitore sua pressão arterial continuamente, dia e noite - sem um manguito inflável. Os manguitos tradicionais capturam apenas um momento, se você se lembrar de usá-los. O Hilo realiza cerca de 25 leituras por dia, revelando como o estresse, as refeições e a atividade afetam sua pressão arterial, para que você possa tomar decisões informadas para o seu bem-estar.
Perguntas frequentes
What specifically caused the reduced brain volume identified in the study?
The study found that an increase in blood pressure between the ages of 36 and 43 was linked to a decreased brain volume. It also indicated that the damage caused by high blood pressure in this context is likely due to changes in blood vessels and the brain's overall structure, rather than the Alzheimer's protein amyloid.
What kind of 'mini-strokes' were observed in the study?
Rises in blood pressure between the ages of 43 and 53 were associated with blood vessel damage or 'mini-strokes' in people over 70. These 'mini-strokes' are a form of damage to the blood vessels in the brain.
Why is it important to check blood pressure earlier than currently recommended?
The study suggests that damage from high blood pressure impacting brain health can occur in early midlife. Current NHS health checks start at age 40, but the research indicates that blood pressure should be measured much earlier to allow for timely intervention and maximise brain health later in life.
How large was the group of people studied?
The research looked at lifelong data from 500 participants. All of these individuals were born in the same week during 1946.
Does high blood pressure cause the Alzheimer's protein to build up?
No, the study found that high blood pressure was not associated with the amount of amyloid protein in the brain. The lead author stated that damage from high blood pressure is unlikely to be driven by the Alzheimer's protein amyloid.
Does managing high blood pressure help prevent dementia?
Yes, high blood pressure in midlife is considered one of the strongest lifestyle risk factors for dementia that can be controlled. Research already suggests that more aggressive treatment of high blood pressure could be improving the brain health of older generations.
Continue lendo abaixo
About the authorView full bio
Ashwin Bhandari
Redator Médico
Bacharelado em Jornalismo
About the reviewerView full bio
Milly Evans
Editora
Milly escreve sobre uma variedade de tópicos de saúde, com um interesse particular em desigualdade na saúde e saúde sexual.
Histórico do artigo
As informações nesta página são revisadas por pares por clínicos qualificados.
21 de ago de 2019 | Última versão
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