Má absorção gastrointestinal
Revisado por Dr Colin Tidy, MRCGPÚltima atualização por Dr Hayley Willacy, FRCGP Last updated 30 Nov 2022
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Nesta série:Doença celíacaDermatite herpetiforme
Gastrointestinal malabsorption syndrome means a failure to fully absorb digested foods from the gut (bowel) into your body. There are many different causes. Prolonged intestinal malabsorption may cause problems because of a lack of carbohydrates, proteins, fats, minerals and vitamins that are essential to keep you healthy.
The treatment will depend on the cause of malabsorption but will also include supplements and other ways to make up for the reduced amount of carbohydrate, protein, fat, minerals and vitamins getting into your gastrointestinal tract.
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What are the symptoms of gastrointestinal malabsorption?
There may be no symptoms if the malabsorption is mild and has not continued for very long. More severe or persistent malabsorption may lead to:
Cansaço (fadiga)
This is because of a lack of energy as you are not absorbing nutrients and essential vitamins and minerals from food.
Perda de peso
If you can't absorb enough energy (calories) from your food then this will cause you to lose weight (and may cause poor growth in children).
Persistent (chronic) diarrhoea
This is a common symptom of persistent malabsorption.
Pale, bulky and smelly stools (steatorrhoea)
This is because there is excessive fat in the stools and they become pale, bulky and very smelly. Fatty stools float and are difficult to flush away. They often leave a greasy rim around the pan.
Intestinal malabsorption may also cause:
Abnormal bleeding, caused by low vitamin K.
Edema, which occurs because of insufficient protein and calories absorbed into the body.
There may also be other symptoms due to the particular underlying condition that is causing the malabsorption.
What are the causes of gastrointestinal malabsorption?
Voltar ao conteúdoThe most common causes in the UK are doença celíaca, Doença de Crohn and chronic pancreatitis. However, the malabsorption of simple carbohydrates affects about 1 in 4 people in Europe. Some diseases associated with malabsorption are found more often in some families - for example, coeliac disease, Crohn's disease, fibrose cística and lactose intolerance.
The causes of gastrointestinal malabsorption include:
Problems with absorbing food from the gut (bowel) into your body
Doença celíaca - a long-term disease that mostly affects the small intestine.
Soya milk intolerance.
Fructose intolerance.
Infection - for example, tuberculose intestinal, diarreia do viajante.
Immune deficiency - for example, infecção por HIV.
Pancreatic insufficiency - for example, fibrose cística, pancreatite crônica, câncer de pâncreas.
Structural causes
Malabsorption may be cause by loss of part of the bowel that is essential to absorb the broken down (digested) food into the body - for example:
Removal of the stomach or part of the bowel after a stomach or bowel operation.
Causes outside the bowel
Exemplos incluem:
Eating disorders: anorexia nervosa, bulimia nervosa.
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Quais testes são necessários?
Voltar ao conteúdoInitial tests will include exames de sangue e stool tests. Further tests may include an abdominal ultrassonografia, barium studies and a tomografia computadorizada (TC) or a exame de ressonância magnética (RM). Any further tests will depend on the likely underlying cause of the intestinal malabsorption.
What are the treatments for gastrointestinal malabsorption?
Voltar ao conteúdoThe treatment will mainly depend on the underlying cause of the malabsorption. However, treatment will also be needed to increase the amount of essential nutrients in the body, including carbohydrates, proteins, fats, minerals and fat-soluble vitamins (nutritional support).
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Leitura adicional e referências
- Zuvarox T, Belletieri C; Malabsorption Syndromes. StatPearls, July 2021.
- Ozaki RKF, Speridiao PDGL, Soares ACF, et al; Intestinal fructose malabsorption is associated with increased lactulose fermentation in the intestinal lumen. J Pediatr (Rio J). 2018 Nov - Dec;94(6):609-615. doi: 10.1016/j.jped.2017.08.006. Epub 2017 Oct 28.
- Montoro-Huguet MA, Belloc B, Dominguez-Cajal M; Small and Large Intestine (I): Malabsorption of Nutrients. Nutrients. 2021 Apr 11;13(4). pii: nu13041254. doi: 10.3390/nu13041254.
- Massironi S, Cavalcoli F, Rausa E, et al; Understanding short bowel syndrome: Current status and future perspectives. Dig Liver Dis. 2020 Mar;52(3):253-261. doi: 10.1016/j.dld.2019.11.013. Epub 2019 Dec 28.
- Brar HS, Aloysius MM, Shah NJ; Tropical Sprue. StatPearls, Jan 2023.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Next review due: 2 Nov 2027
30 Nov 2022 | Última versão
1 Aug 2017 | Publicado originalmente
Escrito por:
Dr Colin Tidy, MRCGP

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